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GLP-2(T)
Dual GIP/GLP-1 Receptor Agonist
MISSION CRITICAL: For in vitro laboratory research only. Not for human or veterinary use. Not evaluated by the FDA. Must be 21+.
SPECIFICATIONS
COMPOUND INTEL
REF #OA-487-GLP2TMOLECULAR PROFILE
GLP-2(T) is a tirzepatide-class dual GIP and GLP-1 receptor co-agonist research peptide with the molecular formula C₂₂₅H₃₄₈N₄₈O₆₈ and a molecular weight of 4813.53 g/mol (CAS: 2023788-19-2), a 39-amino-acid synthetic peptide on a GIP-based backbone bearing a C20 fatty diacid moiety conjugated to Lys20 for albumin binding and extended plasma half-life in preclinical pharmacokinetic models. Studied in pancreatic beta-cell and adipocyte culture systems for concurrent GIP receptor (GIPR) and GLP-1 receptor (GLP-1R) signal transduction. Supplied at ≥99% HPLC purity as a lyophilized powder for in vitro research use only.
MECHANISM OF ACTION
GLP-2(T) engages the GIP receptor and triggers adenylyl cyclase-mediated cAMP elevation in beta-cell and adipocyte culture models.
The same molecule simultaneously activates GLP-1R, enabling study of combined GIPR/GLP-1R cAMP signaling that single-agonist tools cannot replicate.
TECHNICAL DATA
- CAS No.
- 2023788-19-2
- Mol. Formula
- C225H348N48O68
- Mol. Weight
- 4813.53 g/mol
- Purity
- ≥99.0% (HPLC)
- Form
- Lyophilized Powder
- Storage
- −20°C · Lyophilized
